Bustling Genoa, with its commanding position on the Ligurian Sea, has long been one of the most important port cities in Europe. It's the capital of the Liguria region, a major transportation hub, and the gateway to the Italian Riviera. Board a hop-on hop-off tour to learn about the city’s port industrial structures and the ornately decorated buildings in old town (part of which is a designated UNESCO World Heritage Site). Along Via Garibaldi, you’ll see a number of gorgeous palazzi built in the 16th and 17th centuries, some now housing museums. Other highlights worth a stop include one of Europe's largest aquariums, located right on the waterfront; the iconic fountain in Piazza De Ferrari; the Bigo, offering 360-degree views of the city; and the picturesque Lanterna lighthouse. Food tours are a popular option as well, including a visit to the oldest confectionery shop in Europe, family-run since its founding in 1780. For a full immersion into the city’s charms, check out a week-long Italian language and gourmet-food package. Side-trip options include the old fishing town of Boccadasse less than an hour away; the picturesque villages of the Cinque Terre, a 1.5-hour train ride from Genoa; and colorful Portofino, a little less than two hours away by a train-bus combination.