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The refuge is open from dawn until dusk, and the visitor center is open Monday-Friday from 9am-2pm. Summers can be hot and have lots of biting insects (so be sure to bring repellent), and there are free bird walks in fall and winter that are led by refuge staff.
Insider Tip: The refuge is broken up into five different units, and all of the established hiking trails are located inside the Perdue unit. For the best chance of spotting an alligator, head to the observation deck along the Pine Beach trail.