Lake Garda’s towns are fairly widely dispersed around its shores, so consider a convenient, full-day coach tour that covers top sights such as Sirmione and Riva del Garda. Alternatively, break up the day with shorter outings. Ride a motorboat around the Sirmione peninsula, wafting by beaches, the Roman Grotto of Catullus—the relics of the poet’s country villa—and under the bridges of 13th-century Scaligero Castle. Otherwise, cruise north to the more mountainous section of the lake and meander around Garda Island (Isola del Garda), home to the Gothic-style Villa Borghese Cavazza. For a longer sojourn on the water, sail along the quieter west coast, visiting scenic spots such as Salò and Limone sul Garda.

Take advantage of Lake Garda’s geographical position today on a day trip. History and architecture lovers might head to the squares and canals of Venice or to Verona, home to a UNESCO World Heritage Site Roman amphitheater and the house of Juliet, Shakespeare’s fictional star-crossed lover. Also beckoning nearby is Milan, with its world-famous cathedral and designer shopping. Still within day-trip range (but barely) is Florence, cradle of Europe’s Renaissance and home to Michelangelo’s David.

As you’ve covered many of the region’s top sights, devote today to one or two activities of interest. For more history, head for Mantua, a masterpiece of Renaissance town planning and UNESCO World Heritage Site, or, if you’re a nature lover, into Italy’s Dolomite Mountains to visit towns such as Moena and drink in high-altitude views over the peaks of Catinaccio and Marmolada. Alternatively, stay closer to home to enjoy more of Lake Garda’s attractions. Brave a canyoning tour, drive a 3-wheel trike around Garda’s hill villages, or opt for a wine-tasting tour of the Adige Valley, which produces acclaimed Bardolino and pinot grigio. End the day on a private lake cruise that includes appetizers and a glass of prosecco, so you can toast the sunset and soak in Lake Garda’s scenery one last time.