Nisyros (Nisiros) is a popular day trip from Kos or stop on multi-day cruises in the Aegean Sea, which can include free time to explore the island’s highlights independently or an all-inclusive experience with a guide and ground transport on the island. Top attractions include Nisyros’s main town of Mandrakia—a charming waterfront sprawl of white-washed houses and taverna-lined piazzas—set in the hills on the northwest tip of the island, and a clutch of inland Byzantine chapels such as the Church of the Panaghia Faneromeni, accessible via cycling and hiking trails.
The most striking of the island’s cultural sights is the Paliaokastro, high on a hilltop overlooking Mandraki. Dating from the fourth century BC, this was once a mighty acropolis and fort but now little survives except for fragments of the walls constructed out of volcanic basalt, although two towers have been recently remodeled out of rock surrounding the site. In addition, visitors flock to the island’s volcanic caldera and numerous hot springs to take advantage of their healing properties.