San Giovanni Rotondo is located on the Gargano Peninsula in northern Puglia and is a popular day trip and cruise excursion from the nearby port city of Bari. The pilgrimage sites in San Giovanni Rotondo are visited by more than seven million pilgrims every year; only Our Lady of Guadalupe in Mexico City sees more annual visitors.
Tours include a stop at the massive Sanctuary of Saint Pio of Pietrelcina, also known as the Padre Pio Pilgrimage Church. Designed by Renzo Piano and built in 2004, it has seating for 6,500 people inside and a square outside that can fit crowds of up to 30,000. Also included on city tours is the Church of Santa Maria delle Grazie, where Padre Pio, now known as Saint Pio of Pietrelcina, was interred after his death in 1968.