Part of the Los Volcanes complex in the Apaneca-Ilamatepec mountain range, Santa Ana Volcano (also known as Ilamatepec) is one of 23 volcanoes in El Salvador. It takes around an hour and a half of steady uphill hiking to reach the top of the active volcano, which last erupted in 2005—however, due to safety reasons, you must be accompanied by an official guide on the hike.
Guided tours are a great way to skip the 4-hour round trip from Santa Ana by bus, plus the 30-minute hike from the bus stop to the trailhead. You can also organize pickup from other popular destinations around El Salvador, including El Tunco. Some tours also include a visit to nearby Lake Coatepeque for a refreshing, post-hike swim.