There has been a church on this spot since the 12th century, though the current Santuario della Madonna di San Luca dates from the 1700s. San Luca’s roofed arcade, consisting of 666 elegant arches and 15 chapels, was built between 1674 and 1793 to protect the sanctuary’s precious icon during religious processions; today it’s a pretty uphill route climbing the over 900 feet (300 meters) in altitude between the historic center and the church. Once at the church, you can admire a number of important works by artists, including Guido Reni and Guercino, in addition to the famed Madonna and Child icon.
The Santuario della Madonna di San Luca is one of the most important churches in Bologna, and city walking or bike tours often include the trip uphill under its famous covered portico, along with attractions like Piazza Maggiore and the Basilica of San Petronio, the Two Towers, and the churches of Santo Stefano and San Domenico.