This baroque church, designed by Baldassare Longhena, was built in the 17th century and dedicated to the Virgin Mary, or Our Lady of Health, for having brought a stop to a devastating plague outbreak that killed a third of the Venetian population in the early 1600s. You can view its grandeur during a gondola ride or luxury motorboat cruise on the canal, or stop in to admire the Byzantine-influenced interior—with its exquisite mosaic floor and impressive artwork by Tintoretto and Titian—during a Venice walking tour. Private tours often combine a stop at La Salute with other famous sights like St. Mark’s Basilica and the Doge’s Palace in St. Mark’s Square, and the Rialto Bridge (Ponte di Rialto).