Cannaregio, bookended by the Santa Lucia train station and the Rialto Bridge, lines most of Venice’s Grand Canal. Strada Nuova, the district’s busy main street, teems with souvenir shops and tourists; however, meander off into the side streets and canals and you'll soon find peaceful squares (piazzas) and churches.
The best way to explore Cannaregio is by linking up with a walking tour led by a professional guide—someone who knows both the famous monuments and the hidden gems. The biggest attraction here is the Jewish ghetto; tours will also include the area's key churches, Ca' d'Oro Palace, Campo San Leonardo and Campo dei Mori squares, and Ponte delle Guglie (a historic bridge). You can pair small-group and private tours with a gondola ride or a tour of Venice highlights, such as St. Mark's Basilica, the Doge's Palace, and the Rialto Bridge.